Remove / Replace ONLY FIRST Occurrence Of First Character In All Rows Of Column?

I need to remove the first character in each row of a column, but only its first occurrence in each row. For instance:

Say, column 2 has following data (lots of rows, by the way):

First Text" - "blabla"
=SomeText2 = "blabla"
SomeText3 = "blabla"
=SomeText4 = "blabla"
-SomeText5 --- "blabla"
........
....

I would like to use the VBA code to remove ONLY the FIRST occurrence of the FIRST character specified (either "=" or "-") in each row in that column, so that I get:

First Text" - "blabla"
SomeText2 = "blabla"
SomeText3 = "blabla"
SomeText4 = "blabla"
SomeText5 --- "blabla"
......
...and so on...

I tried to use this:

Code:
Columns(2).Cells.Replace What:="-", Replacement:="", LookAt:=xlPart, _
SearchOrder:=xlByRows, MatchCase:=False, SearchFormat:=False, _
ReplaceFormat:=False
Columns(2).Cells.Replace What:="=", Replacement:="", LookAt:=xlPart, _
SearchOrder:=xlByRows, MatchCase:=False, SearchFormat:=False, _
ReplaceFormat:=False
but it replaces ALL occurrences of "=" and "-" and that is not what I need.

I also tried this code:

Code:
With Range("B:B")
.Value = Replace(.Value, "=", "", 1, 1)
End With

But It doesn't work either.