Extract Numbers, PO Box, RR# From Address

I have an excel spreadsheet database displaying 5.000 contact information such as my example below:

Title FirstName LastName Address
Mr adulted it is me 144 picton street e
Ms Moe Scally 1343 university court

What I am trying to do is put 144 in its own column to the left of address and the street name (picton street e) in its own column or the street name to the right of the address column.

Or as in the second example What I am trying to do is put 1343 in its own column to the left of address and the street name (university court) in its own column or the street name to the right of the address column.

In simple terms, this 5,000 enrties need to be sorted by street name only, exluding numbers, possible PO Box, or RR # 3, etc...